Tricyclic antidepressants side effects
The receptor affinities for H1, A1, Muscarinic (m1-6 subtypes) etc determine much of the profile of side effects. This varies a lot between the various available TCAs (see detailed information…
The receptor affinities for H1, A1, Muscarinic (m1-6 subtypes) etc determine much of the profile of side effects. This varies a lot between the various available TCAs (see detailed information…
AbstractThis commentary reviews the tricyclic antidepressants (TCAs) and their place in the treatment of depressive illness, updating information from my seminal review paper on their pharmacology (2007) with data from…
These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, 1. Patients with previous episodes of severe depression (especially if it was unresponsive, or only partially responsive, to…
AbstractThis commentary explains the pharmacology behind the evidence that clomipramine is the most potent and effective of the so-called SNRI antidepressant drugs, and probably the most potent non-MAOI antidepressant drug…