AbstractThis introductory commentary outlines this complex topic, the features of the condition, the drugs that are capable of inducing it (with a genuinely evidence-based table), the patho-physiology, and medical management. The…

AbstractIn the last few decades experimental pharmacology, animal models, in vitro HCR receptor assays, in silico computer modelling, and detailed prospective studies in clinical toxicology, have all provided a comprehensive model…

AbstractThe distinction between NMS and ST continues to generate much poorly informed and confused debate in the literature.  Why, is a puzzle because the evidence is clear that they are…

AbstractThis is the story of how an understanding of the spectrum concept of serotonin toxicity led to my hypothesis, then the experimental validation, of the potent MAO-A inhibitor potency of…