Dr Ken Gillman
Critical independent evaluations in psycho-pharmacology
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Now that the SSRIs have been in use long enough to be seen in perspective it is clear they have side effect differences from the TCAs, with some advantages, albeit…
Sertraline is the logical first choice SSRI. I regard it as perceptibly superior to all the others.Sertraline probably has a significant activity for boosting dopamine, relatively somewhat stronger than venlafaxine’s…
There is accumulating evidence that the SSRIs are less efficacious than TCAs and MAOIs for the treatment of major depression (see summary of Anderson's meta-analysis). This doubt seems to apply…
1. Patients with previous episodes of severe depression (especially if it was unresponsive, or only partially responsive, to an SSRI)2. Those whose current episode is severe or shows psychomotor retardation…
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