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Dr Ken Gillman

Critical independent evaluations in psycho-pharmacology

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Guidelines: problems aplenty

  • Post author:Ken Gillman
  • Post category:Bias in Science
  • Post published: 30 August 2017
  • Post last modified: 2 October 2026

AbstractThis critique is about the problems and adverse treatment consequences associated with medical treatment guidelines.  It explicates the many ways in which they can be, and are, misused, misleading, invalid,…

Continue ReadingGuidelines: problems aplenty

Thinking, Life, Stress and Depression: Pt 2

  • Post author:Ken Gillman
  • Post category:Depressive Illness
  • Post published: 15 November 2016
  • Post last modified: 1 October 2026

AnalogiesI have often been told by patients that the analogies I use to explain things are helpful: I will therefore list some of them here. The symptoms of the illness…

Continue ReadingThinking, Life, Stress and Depression: Pt 2

3. Sibutramine (Reductil) – was it an antidepressant

  • Post author:Ken Gillman
  • Post category:Antidepressants/Newer ADs/SNRIs
  • Post published: 14 November 2014
  • Post last modified: 26 November 2023

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Date Created: about 1998Preface to ‘old edition’Most of the SNRIs that have been on the market have failed…

Continue Reading3. Sibutramine (Reductil) – was it an antidepressant

The Vesicular Monoamine Transporter (VMAT2)

  • Post author:Ken Gillman
  • Post category:General Pharmacology
  • Post published: 14 November 2011
  • Post last modified: 15 February 2026

This commentary is about the intra-neuronal storage of monoamines in vesicles.The vesicular monoamine transporter (VMAT2) is responsible for actively taking up all monoamines (i.e. dopamine (DA), serotonin (5-HT), norepinephrine (NE), epinephrine (EPI) and…

Continue ReadingThe Vesicular Monoamine Transporter (VMAT2)
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Recent Posts

  • Pearl: Causal inference and the ‘do-operator’
    3 May 2026/
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  • Generalisability, external validity
    3 May 2026/
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  • The Credentials of Scientific Evidence Introduction
    3 May 2026/
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  • [NEW] Important Announcement & Update
    6 July 2022/
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  • Project: MAOIs, International Guidelines and WHO ‘Essential Medicines’ Listing
    17 March 2022/
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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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