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Dr Ken Gillman

Critical independent evaluations in psycho-pharmacology

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1. Vortioxetine: Hope or Hype

  • Post author:Ken Gillman
  • Post category:Antidepressants/Newer ADs
  • Post published: 25 April 2021
  • Post last modified: 1 October 2026

In brief This seems to be the latest in a persistently limp and desperate series of ‘new’ anti-depressants with ‘faster-better’ AD action. Evidence for any usefully novel action or efficacy…

Continue Reading1. Vortioxetine: Hope or Hype

2. Bupropion: Still hazy

  • Post author:Ken Gillman
  • Post category:Antidepressants/Newer ADs
  • Post published: 26 September 2016
  • Post last modified: 1 October 2026

Bupropion: Still hazy after all these yearsIntroductionThis note on Bupropion BUP (Wellbutrin etc.) is an update about some new data that is helping to ‘lift the veil of ignorance’ a little further,…

Continue Reading2. Bupropion: Still hazy

3. Sibutramine (Reductil) – was it an antidepressant

  • Post author:Ken Gillman
  • Post category:Antidepressants/Newer ADs/SNRIs
  • Post published: 14 November 2014
  • Post last modified: 26 November 2023

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Date Created: about 1998Preface to ‘old edition’Most of the SNRIs that have been on the market have failed…

Continue Reading3. Sibutramine (Reductil) – was it an antidepressant

4. Electroconvulsive Therapy (ECT). For Whom?

  • Post author:Ken Gillman
  • Post category:Antidepressants/Newer ADs
  • Post published: 1 October 2015
  • Post last modified: 2 October 2026

IntroductionECT is without doubt a safe and effective treatment for serious depression (and other serious psychoses, especially manic depressive illness aka Bipolar disorder). It is under-used and misunderstood still, after…

Continue Reading4. Electroconvulsive Therapy (ECT). For Whom?

Recent Posts

  • Pearl: Causal inference and the ‘do-operator’
    3 May 2026/
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  • Generalisability, external validity
    3 May 2026/
    0 Comments
  • The Credentials of Scientific Evidence Introduction
    3 May 2026/
    0 Comments
  • [NEW] Important Announcement & Update
    6 July 2022/
    0 Comments
  • Project: MAOIs, International Guidelines and WHO ‘Essential Medicines’ Listing
    17 March 2022/
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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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MAOIs: Introductory Comments
MAOI Diet Info Overview
Gillman’s Antidepressants Algorithm
Swapping From One MAOI To Another

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