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Dr Ken Gillman

Critical independent evaluations in psycho-pharmacology

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2. Duloxetine: another SNRI myth

  • Post author:Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published:29 March 2020
  • Post last modified:20 July 2023

Duloxetine does not have a ‘badge-engineered’ metabolite derivative to extend its patent, unlike Venlafaxine (Effexor, now out of patent), and its patent-extending-metabolite, desvenlafaxine.This commentary will be short because it is…

Continue Reading2. Duloxetine: another SNRI myth

1. Venlafaxine: an enduring SNRI myth

  • Post author:Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published:22 March 2020
  • Post last modified:20 July 2023

Venlafaxine (Effexor, now out of patent) and its ‘badge-engineered’ metabolite off-spring (desvenlafaxine, Pristiq- in patent, which is even weaker than venlafaxine as an NRI) are examples of drugs whose attribution…

Continue Reading1. Venlafaxine: an enduring SNRI myth

3. Sibutramine (Reductil) – was it an antidepressant

  • Post author:Ken Gillman
  • Post category:Antidepressants/Newer ADs/SNRIs
  • Post published:14 November 2014
  • Post last modified:20 July 2023

Date Created: about 1998Preface to ‘old edition’Most of the SNRIs that have been on the market have failed to show antidepressant effect in most trials. This drug is a reminder…

Continue Reading3. Sibutramine (Reductil) – was it an antidepressant

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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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