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Dr Ken Gillman, MD

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Duloxetine: another SNRI myth

  • Post author:Dr Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published:March 29, 2020
  • Post last modified:June 18, 2022

Duloxetine does not have a ‘badge-engineered’ metabolite derivative to extend its patent, unlike Venlafaxine (Effexor, now out of patent), and its patent-extending-metabolite, desvenlafaxine.This commentary will be short because it is…

Continue ReadingDuloxetine: another SNRI myth

Venlafaxine: an enduring SNRI myth

  • Post author:Dr Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published:March 22, 2020
  • Post last modified:June 18, 2022

Venlafaxine (Effexor, now out of patent) and its ‘badge-engineered’ metabolite off-spring (desvenlafaxine, Pristiq- in patent, which is even weaker than venlafaxine as an NRI) are examples of drugs whose attribution…

Continue ReadingVenlafaxine: an enduring SNRI myth

Clomipramine: Potent SNRI Anti-Depressant

  • Post author:Dr Ken Gillman
  • Post category:Antidepressants/SNRIs/TCAs
  • Post published:October 11, 2015
  • Post last modified:June 18, 2022

Introduction: 50th birthday tributeClomipramine (CMI) is usually thought of by doctors as a treatment for obsessive-compulsive disorder (OCD). However, it is a potent antidepressant with dual SNRI action (see tables of comparative…

Continue ReadingClomipramine: Potent SNRI Anti-Depressant

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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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