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Critical independent evaluations in psycho-pharmacology

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2. Duloxetine: another SNRI myth

  • Post author:Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published: 29 March 2020
  • Post last modified: 26 November 2023

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Duloxetine does not have a ‘badge-engineered’ metabolite derivative to extend its patent, unlike Venlafaxine (Effexor, now out of…

Continue Reading2. Duloxetine: another SNRI myth

1. Venlafaxine: an enduring SNRI myth

  • Post author:Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published: 22 March 2020
  • Post last modified: 1 October 2026

Venlafaxine (Effexor, now out of patent) and its ‘badge-engineered’ metabolite off-spring (desvenlafaxine, Pristiq- in patent, which is even weaker than venlafaxine as an NRI) are examples of drugs whose attribution…

Continue Reading1. Venlafaxine: an enduring SNRI myth

Gillman’s Antidepressants algorithm

  • Post author:Ken Gillman
  • Post category:Depressive Illness
  • Post published: 19 November 2016
  • Post last modified: 2 October 2026

Gillman’s Antidepressant algorithmSummaryThis commentary presents my antidepressant treatment algorithm which incorporates concepts from Bayesian reasoning and ‘critical path analysis’; that makes it a ‘multi-lane’ clinical pathway. It emphasises procedures which…

Continue ReadingGillman’s Antidepressants algorithm

Recent Posts

  • Tricyclic antidepressants: a further update concerning pharmacology, interactions, and clinical characteristics
    28 October 2026/
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  • Pearl: Causal inference and the ‘do-operator’
    3 May 2026/
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  • Generalisability, external validity
    3 May 2026/
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  • The Credentials of Scientific Evidence Introduction
    3 May 2026/
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  • [NEW] Important Announcement & Update
    6 July 2022/
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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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