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Dr Ken Gillman

Critical independent evaluations in psycho-pharmacology

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2. Duloxetine: another SNRI myth

  • Post author:Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published:29 March 2020
  • Post last modified:26 November 2023

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Duloxetine does not have a ‘badge-engineered’ metabolite derivative to extend its patent, unlike Venlafaxine (Effexor, now out of…

Continue Reading2. Duloxetine: another SNRI myth

Tricyclic antidepressants side effects

  • Post author:Ken Gillman
  • Post category:Antidepressants
  • Post published:1 March 2020
  • Post last modified:5 April 2025

The receptor affinities for H1, A1, Muscarinic (m1-6 subtypes) etc determine much of the profile of side effects.  This varies a lot between the various available TCAs (see detailed information…

Continue ReadingTricyclic antidepressants side effects

Mirtazapine & tranylcypromine: Contrast & irony

  • Post author:Ken Gillman
  • Post category:Bias in Science
  • Post published:26 February 2019
  • Post last modified:15 February 2026

An instance of how an ineffective drug (mirtazapine, Remeron etc.) is over-used and a highly effective one (tranylcypromine, Parnate etc.) is under-used.

Continue ReadingMirtazapine & tranylcypromine: Contrast & irony

Tranylcypromine (Parnate): A Brief History and a Enduring Anomaly

  • Post author:Ken Gillman
  • Post category:Antidepressants/MAOIs
  • Post published:14 November 2014
  • Post last modified:14 February 2026

Progress, far from consisting in change, depends on retentiveness ... Those who cannot remember the past are condemned to repeat itSantayana [1]And Oscar, with his classic nuanced ambiguously interpretable quipsThe…

Continue ReadingTranylcypromine (Parnate): A Brief History and a Enduring Anomaly
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Recent Posts

  • The Credentials of Scientific Evidence
    21 March 2026/
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  • Lithium – Patient information
    14 November 1999/
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  • Lithium – Brief management protocol for doctors
    14 November 2003/
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  • Lamotrigine
    14 November 2008/
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  • Lithium in the Environment, Diet and Body Pt 2
    14 November 2011/
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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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