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Dr Ken Gillman

Critical independent evaluations in psycho-pharmacology

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2. Duloxetine: another SNRI myth

  • Post author:Ken Gillman
  • Post category:Antidepressants/SNRIs
  • Post published:29 March 2020
  • Post last modified:26 November 2023

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Duloxetine does not have a ‘badge-engineered’ metabolite derivative to extend its patent, unlike Venlafaxine (Effexor, now out of…

Continue Reading2. Duloxetine: another SNRI myth

Tricyclic antidepressants side effects

  • Post author:Ken Gillman
  • Post category:Antidepressants
  • Post published:1 March 2020
  • Post last modified:5 April 2025

The receptor affinities for H1, A1, Muscarinic (m1-6 subtypes) etc determine much of the profile of side effects.  This varies a lot between the various available TCAs (see detailed information…

Continue ReadingTricyclic antidepressants side effects

Mirtazapine & tranylcypromine: Contrast & irony

  • Post author:Ken Gillman
  • Post category:Bias in Science
  • Post published:26 February 2019
  • Post last modified:6 May 2025

An instance of how an ineffective drug (mirtazapine, Remeron etc.) is over-used and a highly effective one (tranylcypromine, Parnate etc.) is under-used.

Continue ReadingMirtazapine & tranylcypromine: Contrast & irony

Tranylcypromine (Parnate): A Brief History and a Enduring Anomaly

  • Post author:Ken Gillman
  • Post category:Antidepressants/MAOIs
  • Post published:14 November 2014
  • Post last modified:5 April 2025

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, and include a downloadable PDF.Progress, far from consisting in change, depends on retentiveness ... Those who cannot…

Continue ReadingTranylcypromine (Parnate): A Brief History and a Enduring Anomaly
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Recent Posts

  • Antidepressants – TCAs vs the rest
    13 November 2005/
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  • Tricyclic antidepressants side effects
    1 March 2020/
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  • [NEW] Important Announcement & Update
    6 July 2022/
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  • Taste, Wine, food, and combinations: Advances, and insights from science
    2 March 2020/
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  • Trump, psychopathy, and the Goldwater rule
    13 January 2021/
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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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