PsychoTropical Research | Site-Wide Activity

Ken Gillman wrote a new post

Sun, 03 May 2026 02:50:04 +1000

Pearl: Casual inference and the 'do-operator' THE CREDENTIALS OF SCIENTIFIC EVIDENCE: REBALANCING THE EPISTEMOLOGICAL SCALES 9.2.7 Pearl: Causal inference and the […]

Ken Gillman wrote a new post

Sun, 03 May 2026 02:30:39 +1000

Fisher's fixation and enduring legacy THE CREDENTIALS OF SCIENTIFIC EVIDENCE: REBALANCING THE EPISTEMOLOGICAL SCALES 9.2.6 Fisher’s fixation and enduring legacy Abstract This co […]

Ken Gillman wrote a new post

Sun, 03 May 2026 02:10:14 +1000

The Placebo Effect – meaning or muddle? THE CREDENTIALS OF SCIENTIFIC EVIDENCE: REBALANCING THE EPISTEMOLOGICAL SCALES 9.2.5 The placebo effect: meaning or muddle? phenomenon or […]

Ken Gillman wrote a new post

Sun, 03 May 2026 01:49:43 +1000

Rating Scales THE CREDENTIALS OF SCIENTIFIC EVIDENCE: REBALANCING THE EPISTEMOLOGICAL SCALES 9.2.4 Rating scales: Proxy measures, subjectiveness, and […]

Ken Gillman wrote a new post

Sun, 03 May 2026 01:32:24 +1000

Probability, P-hunting and the null hypothesis THE CREDENTIALS OF SCIENTIFIC EVIDENCE: REBALANCING THE EPISTEMOLOGICAL SCALES 9.2.3 Probability, P-hunting and the null […]

Ken Gillman wrote a new post

Sun, 03 May 2026 00:29:55 +1000

Homogeneity and Simpson’s paradox The Credentials of Scientific Evidence: Rebalancing the Epistemological Scales 9.2.2 Homogeneity and Simpson’s paradox Abstract This co […]

Ken Gillman wrote a new post

Sun, 03 May 2026 00:09:21 +1000

Generalisability, external validity The Credentials of Scientific Evidence: Rebalancing the Epistemological Scales Generalisability, external validity Abstract This commentary, […]

Ken Gillman wrote a new post

Sat, 02 May 2026 23:04:45 +1000

The Credentials of Scientific Evidence Introduction THE CREDENTIALS OF SCIENTIFIC EVIDENCE: REBALANCING THE EPISTEMOLOGICAL SCALESOverview of series Abstract The relative value of different kinds […]

Ken Gillman wrote a new post

Sat, 02 Aug 2025 06:27:31 +1000

Depression: What is it? Why Drug Treatment A great deal has been written on the subject of defining the medical illness of depression. That is not a main theme of this website, nor do I […]

Sophie Duncan wrote a new post

Sun, 04 May 2025 06:16:05 +1000

Introduction to Serotonin Toxicity AbstractThis introductory commentary outlines this complex topic, the features of the condition, the drugs that are capable of inducing it (with a […]

Sophie Duncan wrote a new post

Sat, 05 Apr 2025 21:41:43 +1000

The TCAs Overview and Update AbstractThis commentary reviews the tricyclic antidepressants (TCAs) and their place in the treatment of depressive illness, updating information […]

Ken Gillman wrote a new post

Thu, 05 Dec 2024 09:36:15 +1000

12: Carol's storyIntroduction [KG]As readers might suppose, we hear many stories about patients whose long illnesses have been substantially improved once they […]

Ken Gillman wrote a new post

Thu, 05 Dec 2024 09:25:17 +1000

11: Anxious Annie's StoryIntroduction [KG]When I edit these stories and add an introduction to them, I frequently get into a state where my blood is boiling. This is […]

Ken Gillman wrote a new post

Thu, 05 Dec 2024 08:20:09 +1000

7. Another professor's illness IntroductionThis brief account may be read in conjunction with the preceding account of ‘a professor’s illness’ in this link: […]

Sophie Duncan wrote a new post

Sat, 30 Nov 2024 07:11:38 +1000

RCTs: the great deception Gold-standard or fools-gold?Sigh no more, friends, sigh no more, RCTs were deceivers ever,One foot in SEs and one unsure, to science constant […]

Ken Gillman wrote a new post

Thu, 01 Feb 2024 21:02:30 +1000

Access to MAOIs when not available in your countryThis information should not be taken to suggest or endorse the advisability of people obtaining and taking drugs without adequate medical advice […]

Ken Gillman wrote a new post

Tue, 30 Jan 2024 06:21:38 +1000

1. Beware of what you Read The helpers involved with PsychoTropical periodically relay messages from social media which need correction or modification. I am concerned […]

Ken Gillman wrote a new post

Tue, 05 Dec 2023 03:19:38 +1000

Doctors, guidelines, and patient preference Doctors who find themselves in conflict about practice, as that relates to guidelines, may remind everyone concerned of the statement of the […]

Ken Gillman wrote a new post

Tue, 14 Nov 2023 04:35:54 +1000

2. Hobart Talk and Supplementary Information Hobart talk, Oct 24th 2023. RANZPsych. MAOIs: indications, usage, and interactions The talk itself concentrates general aspects and principles. […]

Ken Gillman wrote a new post

Tue, 14 Nov 2023 03:45:13 +1000

3. Suggested Treatment Pathway to Consider Content coming soon Menu 1. Hobart Talk and Supplementary Information 14 November […]

Ken Gillman wrote a new post

Wed, 25 Oct 2023 00:47:27 +1000

10: A long story of avoidable sufferingIntroduction [KG]This story well illustrates the long periods of unnecessary illness and suffering that many patients experience as result of the […]

Ken Gillman wrote a new post

Wed, 25 Oct 2023 00:44:39 +1000

9. Patient Stories: My Life ReclaimedThere is little to add to this gentleman’s story which is succinct and encapsulates the most common difficulties where doctors simply do not p […]

Ken Gillman wrote a new post

Mon, 07 Aug 2023 07:07:00 +1000

Neuroscience-based criteria for assessing serotonin-mediated effects of drugs These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Neuroscience-based criteria for assessing se […]

Ken Gillman wrote a new post

Tue, 27 Jun 2023 04:30:38 +1000

ST, ergotamine and analogues These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Ergotamine, bromocriptine and LSDThis is an in […]

Ken Gillman wrote a new post

Tue, 27 Jun 2023 04:02:22 +1000

Hyperthermic states and syndromes Normothermia, fever and hyperthermiaThe term ‘hyperthermia’ is used without definition in the general ST literature, and other literature. The […]

Ken Gillman wrote a new post

Tue, 27 Jun 2023 02:33:52 +1000

Selegiline in combination with (S)SRIs These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Selegiline (deprenyl) is selective for MAO-B at th […]

Ken Gillman wrote a new post

Fri, 09 Jun 2023 04:49:28 +1000

Expert medico – legal opinion : CV/BioThese commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, and include a downloadable PDF.Expert opinionsI o […]

Ken Gillman wrote a new post

Mon, 24 Oct 2022 10:18:38 +1000

Stepped trials: Magnifying methodological muddles — the supernatant effect AbstractStepped trials such as STAR*D suffer from a serious methodological flaw. In each stage of the trial one is dealing with a different […]

Ken Gillman wrote a new post

Wed, 28 Sep 2022 06:19:10 +1000

1. Wisdom of the elders These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Book. Treating the Brain: An Odyssey by Barry Bla […]

Ken Gillman wrote a new post

Mon, 15 Aug 2022 07:24:48 +1000

MAOI and TCA combinations: which first? AbstractMany of the myths concerning MAOI drugs can be traced back to the earliest writings from the late 1950s and early 1960s, before anything […]

Ken Gillman wrote a new post

Mon, 15 Aug 2022 07:14:38 +1000

MAOIs – anti-hypertensive effect, history These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, and include a downloadable PDF.IntroductionThis b […]

Ken Gillman wrote a new post

Wed, 27 Jul 2022 11:25:06 +1000

[NEW] Important Announcement & UpdateThe first ever guideline for the use of MAOIs [see here]We have just succeeded in publishing the first ever guideline for the use of MAOIs in […]

Ken Gillman wrote a new post

Wed, 08 Jun 2022 10:51:08 +1000

8. Eric's StoryIntroductionAlthough this text describing Eric’s story is short, the length and extent of his suffering and distress was considerable. It is di […]

Ken Gillman wrote a new post

Sat, 04 Jun 2022 10:35:22 +1000

Dopamine elevation MAO-A, B or both? I particularly acknowledge the assistance of Professor John Finberg in preparing this commentary.IntroductionThere is an enduring lack of […]

Ken Gillman wrote a new post

Sat, 21 May 2022 02:51:39 +1000

Monoamine Oxidase Inhibitors: Perspectives and Pros and Cons AbstractFull details of the interactions between MAOI drugs and other drugs are dealt with separately, and in full detail, in the various other […]

Ken Gillman wrote a new post

Thu, 17 Mar 2022 11:31:35 +1000

ANNOUNCEMENT 11/05/2022On behalf of the PsychoTropical team (Vince, Philip, Lila, Sophie) and the many eminent co-authors of our first ever ‘MAOI treatment guidelines’ paper, I am announcing our new WHO pro […]

Ken Gillman wrote a new post

Wed, 02 Mar 2022 10:52:57 +1000

P-hunting: The illogical in pursuit of the indefensible These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, *A parody on Oscar Wilde [foxhunting: the un […]

Ken Gillman wrote a new post

Fri, 25 Feb 2022 12:56:14 +1000

CNS ‘Stimulants’ and MAOIs Part 2 AbstractThis commentary reviews papers updating knowledge about how MAOI interactions with amphetamine, pseudoephedrine and ephedrine, […]

Ken Gillman wrote a new post

Mon, 21 Feb 2022 11:23:43 +1000

Important news about Low Blood Pressure, MAOIs, and PropranololAbstractPropranolol (predominantly a beta-2 blocker) prevents both the post-dose elevation of blood pressure that some people experience, […]

Philip Dang's profile was updated

Thu, 17 Feb 2022 10:27:22 +1000

Philip Dang's profile was updated

Tue, 08 Feb 2022 12:54:11 +1000

Ken Gillman wrote a new post

Sun, 14 Nov 2021 10:21:12 +1000

Endogenous Lithium & the claimed effect on dementia, suicide etc: A critiqueAbstractPapers by various research groups have suggested relationships between (inter alia) suicide, dementia, and aggressive behaviour, with the […]

Ken Gillman wrote a new post

Sun, 25 Apr 2021 06:00:14 +1000

1. Vortioxetine: Hope or Hype These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, In brief This seems to be the latest in a pe […]

Ken Gillman wrote a new post

Tue, 12 Jan 2021 22:02:43 +1000

Trump, psychopathy, and the Goldwater rule These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, Trump, psychopathy, and the Goldwater ruleThis co […]

Ken Gillman wrote a new post

Sun, 15 Nov 2020 10:36:01 +1000

ECT Controversy: Incomplete evidence and misleading reasoningIntroductionThis is a supplement to my previous commentaries concerning scientific methodology and ECT; those explain why RCTs (Randomised Controlled […]

Ken Gillman wrote a new post

Sun, 02 Aug 2020 02:06:20 +1000

Presentation and Typeface These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, A foolish consistency is the hobgoblin of little mi […]

Ken Gillman wrote a new post

Sun, 02 Aug 2020 02:01:29 +1000

A Comment on Dreyers English These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, A foolish consistency is the hobgoblin of little mi […]

Ken Gillman wrote a new post

Sat, 25 Jul 2020 04:41:22 +1000

MAOIs for psychotic depression — the nature of evidence RCTs are largely sales gimmicks, beguilingly tricked up as a verisimilitude of science~ Ken Gillman 2020After my creation of the above quotation, I […]

Ken Gillman wrote a new post

Mon, 13 Jul 2020 08:30:04 +1000

ECT: Scientific methodology gone wrongAbstractEvidence based medicine, via the vehicles of randomized controlled trials, meta-analysis, and guidelines, has achieved a hegemony in all […]

Ken Gillman wrote a new post

Sat, 02 May 2020 06:25:02 +1000

In briefI would like to draw everyone’s attention to this significant paper by Sven Ulrich and his co-authors for this most useful and significant paper on TCP [1]. For this initial rapid response comment I ma […]