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Dr Ken Gillman

Critical independent evaluations in psycho-pharmacology

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Stepped trials: Magnifying methodological muddles — the supernatant effect

  • Post author:Ken Gillman
  • Post category:Bias in Science
  • Post published:12 June 2019
  • Post last modified:15 February 2026

AbstractStepped trials such as STAR*D suffer from a serious methodological flaw.  In each stage of the trial one is dealing with a different population sample that has a different percentage…

Continue ReadingStepped trials: Magnifying methodological muddles — the supernatant effect

Mirtazapine, a paradigm of mediocre science in a deficient regulatory environment

  • Post author:Ken Gillman
  • Post category:Bias in Science
  • Post published:14 November 2002
  • Post last modified:15 February 2026

AbstractThis commentary summarises the data that indicate the early work published on mirtazapine was inaccurate and misleading.  It points out that there are no data to substantiate the claim that…

Continue ReadingMirtazapine, a paradigm of mediocre science in a deficient regulatory environment

APA textbook update: MAOIs

  • Post author:Ken Gillman
  • Post category:Bias in Science
  • Post published:10 October 2017
  • Post last modified:15 February 2026

APA textbook — serious errorsIntroductionIn August of 2016, I posted some observations about serious errors in the APA textbook of psychopharmacology (4th ed.). I communicated my concerns to the editor, Dr…

Continue ReadingAPA textbook update: MAOIs

Risperdal: Forgotten Chicanery

  • Post author:Ken Gillman
  • Post category:Anti-Psychotics/Bias in Science/For Review
  • Post published:25 March 2017
  • Post last modified:15 February 2026

This commentary incorporates suggestions for combatting the tidal waves of bad and dishonest science, flooding over us all via the medical journals that we read. Quite a long time ago…

Continue ReadingRisperdal: Forgotten Chicanery
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Recent Posts

  • Generalisability, external validity
    3 May 2026/
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  • The Credentials of Scientific Evidence Introduction
    3 May 2026/
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  • Pearl: Casual inference and the ‘do-operator’
    3 May 2026/
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  • Lithium – Patient information
    14 November 1999/
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  • Lithium – Brief management protocol for doctors
    14 November 2003/
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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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