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Dr Ken Gillman

Critical independent evaluations in psycho-pharmacology

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The TCAs Overview and Update

  • Post author:Sophie Duncan
  • Post category:Antidepressants/TCAs
  • Post published:6 April 2025
  • Post last modified:6 April 2025

AbstractThis commentary reviews the tricyclic antidepressants (TCAs) and their place in the treatment of depressive illness, updating information from my seminal review paper on their pharmacology (2007) with data from…

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Clomipramine: Potent SNRI Anti-Depressant

  • Post author:Ken Gillman
  • Post category:Antidepressants/TCAs
  • Post published:11 October 2015
  • Post last modified:6 April 2025

AbstractThis commentary explains the pharmacology behind the evidence that clomipramine is the most potent and effective of the so-called SNRI antidepressant drugs, and probably the most potent non-MAOI antidepressant drug…

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Migraine & melancholic depression

  • Post author:Ken Gillman
  • Post category:Depressive Illness
  • Post published:20 November 2016
  • Post last modified:2 August 2025

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, and include a downloadable PDF.SummaryThere is an association of migraine with serious depression, encompassing the linked domains…

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Recent Posts

  • Lithium in the Environment, Diet and Body Pt 1
    14 November 2011/
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  • Lithium – Patient information
    14 November 1999/
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  • Lithium – Brief management protocol for doctors
    14 November 2003/
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  • Dietary Lithium: A critique of the claimed effect on depression and suicide
    23 February 2019/
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  • Lithium levels in tap-water & suicide
    12 August 2017/
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PsychoTropical is a knowledge and education resource started by Dr Gillman about 20 years ago. It is neither connected with, nor influenced by, any financial backing or interest group of any sort. The opinions expressed relate to Dr Gillman’s special knowledge and expertise as a recognised world-expert in MAOIs and serotonin toxicity.

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MAOIs

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MAOIs: Introductory Comments
MAOI Diet Info Overview
Gillman’s Antidepressants Algorithm
Swapping From One MAOI To Another

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